They play an important role in reducing the flare-upreactions in conglobate acne and for the reduction of gran-uloma pyogenicum-like lesions under isotretinoin treat-ment.
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The skin of certain sensitive individuals may become excessively rededematousblisteredor crustedIf these effects occurthe medication should either be discontinued until the integrity of the skin is restoredor the medication should be adjusted to a level the patient can tolerateTrue contact allergy to topical tretinoin is rarely encounteredTemporary hyperor hypopigmentation has been reported with repeated application of RETIN-ASome individuals have been reported to have heightened susceptibility to sunlight while under treatment with RETIN-ATo dateall adverse effects of RETIN-A have been reversible upon discontinuance of therapysee DOSAGE AND ADMINISTRATION Section
Important Safety Information for Obagi-C Rx C-Clarifying Serum and C-Therapy Night Cream.
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furthermore, tretinoin indirectly inhibits matrix metalloproteinases mmp , the enzymes that break down collagen and elastin, the skin s key structural proteins.