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To reduce the risk of dizziness and lightheadednessget up slowly when rising from a sitting or lying position.

Triamterene can cause a loss of too much body waterdehydrationand salt/mineralsTell your doctor right away if you have any symptoms of dehydration or mineral losssuch as confusionunusual dry mouth/thirstfast/irregular heartbeatsevere dizziness/lightheadednessor seizures.

This fixed combination drug is not indicated for the initial therapy of edema or hypertension except in individuals in whom the development of hypokalemia cannot be risked.

In patients requiring hydrochlorothiazide therapy and in whom hypokalemia cannot be risked therapy may be initiated with MAXZIDE-25 MGIf an optimal blood pressure response is not obtained with MAXZIDE-25 MGthe dose should be increased to two MAXZIDE-25 MG tablets daily as a single doseor one MAXZIDE tablet dailyIf blood pressure still is not controlledanother antihypertensive agent may be addedsee PRECAUTIONSDRUG INTERACTIONS

Thiazides and triamterene in combination have not been studied in nursing mothersTriamterene appears in animal milk and this may occur in humansThiazides are excreted in human breast milkIf use of the combination drug product is deemed essentialthe patient should stop nursing.

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triamterene-induced hyperkalemia can cause life-threatening cardiac arrhythmias and is more likely to occur in patients with impaired renal function, diabetes mellitus, or in geriatric patients; these patients should have periodic serum electrolyte, creatinine, and bun levels monitored.